OGT has over 20 patent families covering areas that are relevant to the biological sciences such as microarrays and genomics.
Some of the patent families actively out-licensed by OGT are detailed below:
Family 1 - Analysing polynucleotide sequences (WO89/10977)
This patent family covers oligonucleotide microarrays, their manufacture and their use for the analysis of polynucleotide sequences. These fundamental patents are also referred to as the “Southern Array Patents”.
Family 2 - Support-bound oligonucleotides (WO90/03382)
These patents describe the use of a covalent phosphodiester link for attaching nucleic acids to solid supports. The link is easy to synthesise and is stable under de-protection conditions. The link is formed between a terminal phosphate group of a nucleos
Family 6 - Detecting sequence variations (WO96/31622)
The patents in this family describe the use of microarray technology to detect variations in DNA sequences e.g. SNPs or different lengths of tandem repeat regions. Target nucleic acids hybridise to probes on an array and are extended through ligation or c