Custom Microarray Services » CGH » Customised aCGH

OGT customised aCGH microarrays

OGT's aCGH service allows researchers to use CGH arrays to analyse specific areas of the genome at high resolution. It is ideal if a customer knows or suspects a deletion or amplification is present at a particular location, but would like to know the precise coordinates of this aberration.

Summary of the OGT CGH service

  1. Design and optimisation of the array probes to any location in any sequenced genome
  2. Fabrication of the customised oligonucleotide CGH arrays using ink jet in-situ synthesis
  3. Labelling of customer genomic DNA samples
  4. Hybridisation, washing and scanning of OGT CGH microarrays
  5. Data analysis and interpretation

Advantages of the OGT array CGH service

  • We offer a comprehensive consultancy CGH service from experimental design through all stages to data analysis and interpretation
  • A flexible approach ensures that OGT will design and optimise probes to your specification Probes may be designed to specific genes, exons or a targeted region of the genome
  • Fabrication using ink jet in-situ synthesis (IJISS) provides
    • high quality microarrays at a cost effective price
    • flexible synthesis technology which allows you to evaluate each array design and make changes as required
  • Long 60mer oligonucleotide microarrays results in higher sensitivity, generating information rich data
  • A high probe density allowing high resolution or several regions to be studied simultaneously
  • No sample PCR amplification reduces preparation time
  • Two colour microarrays enable test and control samples to be hybridised on the same array saving valuable time and experimental costs
  • Gives you the choice to run the microarray experiments in your laboratory or ours
  • We can supply as few as one custom microarray or as many as hundreds in a cost-effective manner
  • We have experience in data interpretation from CGH experiments enabling you to understand the significance of your data
  • We offer training in the microarray techniques required for CGH experiments at our laboratory in Oxford

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