CytoSure™ Interpret Software

CytoSure Interpret Software is a powerful and easy-to-use package for the analysis of aCGH data, offering an impressive combination of features that allow you the choice of standardised data analysis (using the Accelerate Workflow) or customised, user-defined data analysis. Groundbreaking new functionality allows effortless identification of both copy number variation (CNV) and uniparental disomy (UPD) when used in conjunction with the new CytoSure ISCA UPD array. CytoSure Interpret Software is exclusively provided with OGT’s extensive range of CytoSure aCGH arrays. 

CytoSure Interpret Software delivers:

• Fast and simple analysis of aCGH data
• Direct links to external databases and online resources
• Extensive customisation options to meet the needs of your laboratory
• Constant innovation ensuring class-leading data interpretation

Ordering information

Fast and simple analysis of aCGH data

CytoSure Interpret Software utilises an innovative “Accelerate Workflow” that provides automated data analysis based on predefined settings. This unique feature minimises the need for user intervention and maximises the consistency and speed of the data analysis. The analysis time is further reduced by using a batch processing facility, which allows an unlimited number of samples to be analysed simultaneously using a Circular Binary Segmentation (CBS) algorithm for identifying chromosomal abnormalities. In addition, the bulk load feature allows faster sample loading as multiple sets of sample information can be loaded at once as a text file.

Figure 1: Automated aberration detection with CytoSure analysis software, showing clear detection of chromosomal abnormalities

Direct links to external databases and online resources

CytoSure Interpret Software includes extensive annotation tracks covering syndromes, genes, exons, CNVs and recombination hotspots — each of which link to publicly available databases such as Decipher and the Database of Genomic Variants, providing results in context. In addition, CytoSure Interpret Software seamlessly integrates with Cartagenia’s BENCH™ software, allowing users to securely transfer CNV calls for aCGH aberration data management and genotype-phenotype correlation, providing greater confidence in the calls made.

Extensive customisation options to meet the needs of your laboratory

CytoSure Interpret Software gives you the flexibility to optimise software settings for your laboratory's needs as well as the freedom to customise your data report to show only the information you need. 

Dr. Agne Liedén from the Department of Molecular Medicine and Surgery, Karolinska Institutet commented:

" I recently integrated the new CytoSure Interpret Software into my laboratory workflow. I have been extremely impressed with the ease-of-use and flexibility of the software. In our experience, OGT is very responsive to customer feedback and they have already implemented several of our suggested improvements. OGT has indeed produced an excellent software package that should become a useful tool for cytogeneticists and molecular geneticists."

Constant innovation ensuring class-leading data interpretation

Constant innovation ensures that CytoSure Interpret Software remains the class-leading aCGH analysis software. Our dedicated software development team are continually implementing enhanced features and capabilities in response to new product development and customer feedback. 

To complement the CytoSure ISCA UPD array, CytoSure Interpret Software can now identify DNA regions exhibiting loss of heterozygosity (LOH), whole chromosome uniparental disomy (UPD) and segmental UPD. In addition, potential mosaicism can now be detected using our specialised threshold factors. Another unique feature is the facility to identify sample mix-up when used in conjunction with CytoSure ISCA Sample Tracking Spike-ins — providing confidence in results. These constant innovations ensure you can rely on CytoSure Interpret Software to provide fast and reliable delivery of meaningful results.

Ordering information

CytoSure™ products are for research use only.