Products » ChIP » Prokaryotic

ChIP » Prokaryotic

Chromatin Immunoprecipitation (ChIP) is a well-established and reliable method used to identify the DNA binding site of a protein of interest. Chip2 ™ microarray products combine the strengths of OGT microarrays with chromatin immunoprecipitation. Chip2 microarrays are a powerful technique that can be used to analyse and identify the precise positions on the genome where DNA:protein interactions occur.

Use Chip2 microarrays to:

  • Identify the binding positions of global DNA binding proteins
  • Analyse changes in a particular protein's binding under various environmental conditions.
  • As a model system to further understand gene regulation
  • Reveal potential therapeutic targets against these Prokaryotic species

Chip2 microarray products from OGT offer:

  • The ability to screen whole Prokaryotic genomes on one array at high resolution
  • High sensitivity resulting from the use of validated 60mer oligonucleotide microarrays
  • High quality microarrays at a cost effective price fabricated using the latest technology
  • Reduced preparation time as the sample requires no PCR amplification
  • Two colour microarrays enabling test and control samples to be hybridised on the same array saving valuable time and experimental costs.

Diagram of Chip2 protocol (click here)

Chip2 microarray products available

Product Product Code Background
Chip2 E.coli K12
4 x 44K format		 010010 Developed and validated with Professor Busby at the Uni. of Birmingham, UK
Chip2 E.coli 0157
4 x 44K format		 010011 Developed and validated with Professor Penn at the Uni. of Birmingham, UK
Chip2 Salmonella typhimurium LT2
4 x 44K format		 010020 Developed and validated with Professor Hinton at the Institute of Food Research, Norwich, UK
Chip2 Salmonella typhimurium SL1344
4 x 44K format		 010021 Developed and validated with Professor Hinton at the Institute of Food Research, Norwich, UK
Chip2 Streptomyces coelicolor 010040 Developed and validated with Professor Smith at the Uni. of Surrey, UK

To view recent ChIP publications click here

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