Target identification

OGT offers a wide range of biomarker discovery technologies, enabling clients to choose the most appropriate and effective method for target identification.  We work with clients to develop the optimal study design, sample processing protocols, data analysis pathways, and biomarker identification / validation strategies.  We provide both focused and genome-wide target identification services working from a wide range of biological samples. 

OGT’s target identification services deliver:

• Cost-effective customised solutions
• Comprehensive choice of analytes
• A wide choice of technologies
• Dedicated and experienced project teams

Cost-effective customised solutions

We offer rapid screening and validation services for target identification. Our in-house design capabilities enable customised solutions based on your specific requirements.  Our project teams deliver high throughput, high quality data from accredited  laboratories.  We work with a wide variety of biological samples (e.g. serum, plasma, faeces, urine, tissue, etc) and species.

Comprehensive choice of analytes

We offer clients a comprehensive choice of technologies for studying different analytes: 

DNA

• Single Nucleotide Polymorphisms (SNPs)
• Copy Number Variation (CNVs)
• Methylated DNA (mDNA)
• DNA sequencing (NGS)

RNA

• Messenger RNA (mRNA)
• microRNA (miRNA)

Protein

• Autoantibody
• Protein

Wide choice of available technologies

Our comprehensive range of technologies are tailored to suit the needs of each individual client:

Microarray (DNA & protein)

• Genome-wide arrays (non-hypothesis driven) for screening  
• Custom designed focused arrays (hypothesis driven) for validation

Next generation sequencing

• Genome-wide sequencing (non-hypothesis driven) for screening
• Custom designed selective sequencing (hypothesis driven) for validation

Quantitative PCR (qPCR)

• Custom designed focused qPCR (hypothesis driven) for validation

ELISA

• Selective validation (hypothesis driven)

Dedicated and experienced project teams

Our highly skilled project teams rapidly deliver tailored  target identification programmes based on the specific needs of each individual client. Our in-house team of molecular biologists, computational biologists and protein chemists complement client project teams to deliver novel, validated clinical targets.